Biocatalysis

What we offer

  • Scale-up and demonstration of biocatalytic processes, using purified enzyme and whole-cell biocatalysts
  • Bioconversion processes (see fermentation folder)
  • Process development and optimization
  • Food grade production (FSSC22000)
  • First series compound production and custom manufacturing at 15000 L scale
  • Immobilization of enzymes and whole cells
  • Aqueous and solvent-based reactions
  • Production of enzymes through bacterial, yeast or fungal fermentation
  • Process design

Biocatalysis equipment overview

  • Bench-scale reactors
  • Multiple mobile reactors in the range of 20-1000 L
  • Aerated reactors (see fermentation folder)
  • Reaction vessels for slurries with high solids contents: 2 x 500 L
  • 2 x 4000 L
  • 2 x 5000 L
  • 4 x 8000 L
  • 2 x 14500 L
  • 1 x 20000 L
  • 4 x 24000 L
  • 3 x 50000 L
  • 1 x 20 L (ATEX)
  • 1 x 85 L (ATEX)
  • 1 x 250 L (ATEX)
  • 1 x 500 L (ATEX)
  • 1 x 1000 L (ATEX)
  • 1 x 5400 L (ATEX)
  • Fermenters of different sizes to produce the biocatalyst (see fermentation folder)
  • Enzyme purification equipment: cross-flow membrane filtration (MF, UF, NF in different scales ranging from bench to 10000 L scale, see product recovery and purification folder)
  • A variety of downstream purification equipment to purify the product of interest from the reaction mixture (see product recovery and purification folder)
  • 4 x 30000 L (ATEX, solvent)

Expertise

BBEPP’s team of process and R&D engineers has built up a significant track record in production of biocatalysts and in biocatalytic conversions at lab and pilot scale. The team has demonstrated various aqueous and solvent-based reactions at an industrially relevant scale.