How to cross the biotech Valley of Death and manage the bumpy road to scaling bio-based innovations?

On June 19th, 2025  bioCircular Loop issued episode 15 of its bioeconomy podcast series.

In this episode of the bioCircular Loop podcast, Melina Gerdts discusses the challenges biotech start-ups face in scaling their innovations from lab to industrial scale with Hendrik Waegeman, Head of Operations at the Bio-Base Europe Pilot Plant. They explore the high costs associated with scaling, the importance of collaboration and expertise, and the regulatory hurdles that can delay market entry. The conversation also highlights emerging trends in biobased applications, including alternative proteins, biopesticides, and food colorants. In this conversation, Hendrik Waegeman discusses the evolution of the bioeconomy, focusing on the transition to natural colorants, the complexities of biofuels, and the scaling of bio-based infrastructure in Europe. He highlights the international nature of their customer base, investment trends, and the regulatory challenges faced in the sector. Despite these challenges, he expresses optimism for the future of bio-based innovation, emphasizing the impact of BBEPP on sustainability and innovation in the bioeconomy.

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