ChitoBioEngineering

The ChitoBioEngineering project aims at establishing biotechnological ways of producing fully defined, partially acetylated chitosan oligomers. This will be achieved through genetic, metabolic, and enzyme engineering.

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DemoProBio

Industrial biotechnology plays a crucial role in the development of sustainable and cost effective production processes for biobased chemicals. These processes typically consist of two distinct unit operations: fermentation, followed by purification of the compound of interest from the fermentation broth. Product recovery and purification (also called downstream processing or DSP) are important cost factors, responsible for up to 80% of the total production cost. Reducing DSP cost is therefore a key success factor to improve the overall economics of biobased processes.

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Novosides

The goal of the Novosides project is the development of biocatalytic processes for the glycosylation of small organic molecules such as flavonoids, alkaloids and steroids. Glycosylation can drastically improve both the physicochemical and biological properties of these molecules (e.g. slow release, improved solubility and stability, taste modification, drug targeting), but few biocatalysts are currently available to perform this modification cost-efficiently at industrial scale.

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